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| Diuretics |
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| Potassium-Sparing
Diuretics |
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| Depletions |
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| Calcium |
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Osteoporosis (bone loss) is the primary disease associated
with long-term calcium deficiency; it may be associated with
bone pain and spinal deformity. Depleted levels can also cause
muscle cramps, irregular heartbeat, and depression.
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| Vitamin
B9 (Folic Acid) |
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Low levels of folic acid have been linked to anemia, heart
disease, and birth defects.
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| Editorial Note |
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The selected depletions information presented here identifies
some of the nutrients that may be depleted by certain
medications. The signs and symptoms associated with nutrient
deficiency may also indicate conditions other than nutrient
deficiency. If you are experiencing any of the signs or symptoms
mentioned, it does not necessarily mean that you are nutrient
deficient. Nutrient depletion depends upon a number of factors,
including your medical history, diet, and lifestyle as well as
the length of time you have been taking the medication. Please
consult your healthcare provider; he or she can best assess and
address your individual healthcare needs, and determine if you
are at risk for nutrient depletions from these medications as
well as others not listed here.
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| Supporting Research |
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Ames BN. Micronutrient deficiencies: A major cause of DNA
damage. Ann NY Acad Sci. 2000;889:87-106.
Cashman K, Flynn A. Optimal nutrition: calcium, magnesium and
phosphorus. Proc Nutr Soc. 1999;58:477-487.
Covington T, ed. Nonprescription Drug Therapy Guiding
Patient Self-Care. St Louis, MO: Facts and Comparisons;
1999:467-545.
D'Arcy PF. and Griffin JP. Iatrogenic Diseases.
London, Oxford U. Press, 1972.
Potts JT. Diseases of the parathyroid gland and other hyper-
and hypocalcemic disorders. In: Fauci AS, Braunwald E,
Isselbacher KJ, et al, eds. Harrison's Principles of Internal
Medicine. 14th ed. New York: McGraw-Hill
Companies Health Professional Division; 1998:2241.
Tuckerman M. and Turco S. Human Nutrition.
Philadelphia, Lea and Febiger, 1983; 215-222.
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| Review Date: October
2000 |
Reviewed By: All
depletions monographs have been reviewed by a team of experts
including Derrick M. DeSilva, Jr., MD, Raritan Bay Medical
Center, Perth Amboy, NJ; Jacqueline A. Hart, MD, Department of
Internal Medicine, Newton-Wellesley Hospital, Harvard University
and Senior Medical Editor, A.D.A.M., Inc., Boston, MA; John
Hinze, PharmD, NMD, Woodbine, IA; Ruth Marlin, MD, Medical
Director and Director of Medical Education, Preventive Medicine
Research Institute, Sausalito, CA; Brian T Sanderoff, PD, BS in
Pharmacy, Clinical Assistant Professor, University of Maryland
School of Pharmacy; President, Your Prescription for Health,
Owings Mills, MD; Leonard Wisneski, MD, FACP, George Washington
University, Rockville, MD; Ira Zunin, MD, MPH, MBA, President
and Chairman, Hawaii State Consortium for Integrative Medicine,
Honolulu, HI.
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Copyright © 2004 A.D.A.M., Inc
The publisher does not accept any
responsibility for the accuracy of the information or the
consequences arising from the application, use, or misuse of any
of the information contained herein, including any injury and/or
damage to any person or property as a matter of product
liability, negligence, or otherwise. No warranty, expressed or
implied, is made in regard to the contents of this material. No
claims or endorsements are made for any drugs or compounds
currently marketed or in investigative use. This material is not
intended as a guide to self-medication. The reader is advised to
discuss the information provided here with a doctor, pharmacist,
nurse, or other authorized healthcare practitioner and to check
product information (including package inserts) regarding
dosage, precautions, warnings, interactions, and
contraindications before administering any drug, herb, or
supplement discussed herein.
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